First-aid measures after ingestion : Rinse mouth with water. Chloroform Carbon dioxide (CO2) Hydrogen chloride gas Phosgene Thermal decomposition can lead to release of irritating gases and vapors Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Exposure to chloroform may also cause cancer. contaminated clothing before re­use. touching a finger to the back of the throat or by administering Embryotoxin, do not allow pregnant staff to handle chloroform. Chloroform (CHCl3) is a colorless liquid that quickly evaporates into gas. google_color_url = "215670"; Show this safety data sheet to the doctor in attendance. Chloroform is incompatible with: Chloroform is used in many industries. //-->, SYNONYMS Potential human carcinogen. Remove contaminated clothing and Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Let the instructor know immediately about any glassware breakage or chemical spills that may occur so that proper cleanup procedures can be instituted. affects the central nervous system. powder ­ produces explosions ranging from violent to mild. Useful search terms for chloroform include “methane trichloride” and “trichloromethane.”. SECTION 6 : Accidental release measures Personal precautions, protective equipment and emergency procedures: Ensure adequate ventilation.Ensure that air-handling systems are operational. Search the HHE database for more information on chemical topics. Wash the spill site with a soap solution. alcoholic drinks will enhance the toxicity of chloroform. Trichloromethane, methane trichloride, methanyl trichloride, 121: Chloroform, OECD Global Portal to Information on Chemical Substances, National Institute for Occupational Safety and Health, U.S. Department of Health & Human Services, Workers involved in paper manufacture or recycle industries, Service employees exposed to some air conditioner refrigerants, Equipment operators working at sanitary landfills, Workers who work in water treatment plants. 1,000 ppm in the atmosphere is toxic and may cause water until all evidence of the chemical has been removed Seek Chloroform is an animal carcinogen and suspected of being a Severe exposure can cause liver and/or kidney damage, skin burns, tremor, convulsions, and twitching. self­contained breathing apparatus. google_ad_channel = "2166881430"; Chloroform is used in some refrigerants, solvents, and chemical manufacturing. If breathing is difficult give oxygen. control the level of exposure to below recommended limits. handled by pregnant staff members. The toxic liquid compounds concerned here are insoluble in water Work in a well-ventilated area (preferably in an environment with a fume extraction system). phosgene. 77, No. combustion. Some symptoms of exposure to phenol are weight loss, weakness, exhaustion, muscle aches, and pain. comfortable position, then keep warm. The Health Hazard Evaluation Program (HHE) conducts onsite investigations of possible worker exposure to chemicals. STORAGE Toxicity and Safe Handling Please refer to the current Safety Data Sheet (SDS) prior to working with chloroform. Wear protective clothing. google_ad_client = "pub-7080753133094481"; Unlike in alcohols where the hydroxyl group is bound to a saturated carbon atom, in phenols the hydroxyl group is attached to an unsaturated aromatic (alternating double and single bond) hydrocarbon ring suc… The level of exposure depends upon the dose, duration, and work being done. //2007-09-16: IHC-Ellis-Bottom avoid exposure to yourself. Skin penetration may occur. Chloroform-d (Deuterochloroform, CDCl 3), deuterated chloroform, is a standard purity solvent for NMR (Nuclear Magnetic Resonance) analyses. Chloroform can be toxic if inhaled or swallowed. Corrosive effects have been observed, but only following prolonged application, like for 24 hours. google_color_bg = "FFFFFF"; P273 Avoid release to the environment. Workers may be harmed from exposure to chloroform. COVID-19 is an emerging, rapidly evolving situation. Safety and environmental precautions 2 Employee Information and Training Employees who handle formaldehyde must receive documented training on the hazards of formaldehyde and what to do in case of an exposure or spill. Reactions to an excessive inhalation exposure include headache, dizziness, drunkenness, nausea, and loss of consciousness. P264 Wash skin thoroughly after handling. Allow the patient to assume a google_ad_type = "text_image"; dizziness, intracranial pressure and nausea. and hydrochloric acid. google_ad_height = 600; Chloroform will attack some plastics and rubber. google_color_link = "003366"; wash the affected area with soap or mild detergent and large Immediately after ingestion: give lots of water to … alkalis and incompatible substances. Page 2 of 14 Research and Occupational Safety ... Safety Specialist at 206-543-7388 for guidance or to request that air monitoring be conducted P264 Wash skin thoroughly after handling. Allow to rest until fully Firefighting instructions : Cool tanks/drums with water spray/remove them into safety. The level of exposure depends upon the dose, duration, and work being done. The vapour is heavier than air and will collect in Always wear gloves, goggles, cap and face mask. google_ad_format = "160x600_as"; Chloroform can be absorbed through the skin, based on animal information. Chloroform CX1050 2/8 Composition/information on ingredients Name CAS number % by weight 3 . Dilute toxic gases with water spray. Acute exposure to the skin may Keep in mind that chloroform will penetrate nitrile gloves in less than 2.5 minutes. 58 / Monday, March 26, 2012 / Rules and Regulations 03/12/2019 EN (English US) 3/12 . sodium hydroxide with chloroform will explode on impact. explosion will occur. //2007-09-16: IHC-Ellis-Top Visit NIOSH’s page on Managing Chemical Safety in the Workplace to learn more about controlling chemical workplace exposures. The minimum PPE for work with chloroform is Viton or PVA (Polyvinyl Acetate) laboratory gloves, lab coat, and safety glasses (ANSI/ISEA Z87.1 approved). Store out of sunlight. long sleeved laboratory coat or gown, rubber gloves, safety //-->, BACK to the P280 Wear eye protection/ face protection. Ingestion ­ if the patient is conscious induce vomiting by Persons with a pre­existing liver, kidney, skin or heart disease Seek immediate medical advice. cause mild irritation to severe erythema and purulent blebs. Here we prepare chloroform for use as a solvent. //-->, Home | 4,000 ppm will produce symptoms of vomiting, fainting and Potassium­sodium alloy ­ violent explosion. may be at an increased risk. methyl trichloride, trichloroform, formyl trichloride. P271 Use only outdoors or in a well-ventilated area. In case of skin contact Proper safety precautions should be taken and this reaction must be done outside or in a fume hood. 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