Not all pack sizes may be distributed in Australia. Bulk Orders will have our Online Team be in touch in order to discuss appropriate shipping costs. CAS: 70359-46-5. Product should be applied smoothly and evenly across your face in a thin layer. If outdoors, wear protective clothing and use a non-comedogenic, broad spectrum, SPF 50+ sunscreen. Keep these telephone numbers handy. Monoamine oxidase (MAO) inhibitors may interfere with the metabolism of brimonidine and potentially result in an increased systematic side effect such as hypotension. Hands should be washed after applying MIRVASO. We offer Standard Shipping for $4.95** with approximately 3-6 business days of transit time based upon your location within Australia. digoxin), used to treat heart problems. Hypersensitivity to the active substance or to any of the excipients; children under 18 years of age; therapy with concomitant monoamine oxidase inhibitor (MAOI), tricyclic or tetracyclic antidepressants, which affect noradrenergic transmission. methylphenidate or Ritalin). blood pressure lowering medicine such as beta-blockers or calcium channel blockers (e.g. Mirvaso should be applied to the face only. Keep out of your mouth, nose, and eyes (may burn). In the rare instance you've had an allergic reaction to a product, please discontinue use of the product immediately. Concomitant use of Mirvaso with other medicinal products for the treatment of rosacea has not been systematically investigated. Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop. Overall, Mirvaso gel was shown to be well tolerated, with the most commonly (i.e. If you have any concerns about taking this medicine, ask your doctor or pharmacist. **These delivery costs do not represent orders that we consider 'Bulk Orders'. No more than 1 g of gel per day should be used, and application to the eyes, eyelids, lips, mouth and membrane of the inner nose should also be avoided. Making safe and wise decisions for biological disease-modifying antirheumatic drugs (bDMARDs) and other specialised medicines. Sometimes they are serious, most of the time they are not. You may need to read it again. Mirvaso is indicated for the treatment of facial erythema of rosacea in adult patients. Tell all doctors and pharmacists who are treating you that you are using MIRVASO. 1-16 of 46 results for "brimonidine gel" Skip to main search results Eligible for Free Shipping. Read our privacy policy. Do not get it in your eyes, nose, or mouth. Nardil, Parnate) or tricyclic antidepressants (such as imipramine) or tetracyclic antidepressants (such as maprotiline, mianserin or mirtazapine). Do not use MIRVASO to treat any other complaint unless your doctor tells you to. Tell all doctors and pharmacists who are treating you that you are using MIRVASO. It is recommended that MIRVASO be applied once per day after your usual cleansing routine, and before any cosmetics or sunscreen are applied. Call 1300 463 342 if you would like to confirm available quantities. 58 Richard Pearce Drive Prescription product orders will be dispensed and dispatched on the business day the prescription or valid repeat authorisation is received at the SUPERPHARMACY registered premises. The efficacy of Mirvaso in the treatment of moderate to severe facial erythema of rosacea has been demonstrated in two randomised, vehicle controlled clinical trials, which were identical in design. A Customer Service Team Member will then review your request, and be in touch with some further information. methylphenidate or Ritalin). This leaflet answers some common questions about MIRVASO. Your doctor will tell you how long to use MIRVASO. Ongoing education for Aboriginal and Torres Strait Islander health workers and practitioners on quality use of medicines and medical tests, Practical information, tools and resources for health professionals and staff to help improve the quality of health care and safety for patients. Mirvaso ® (brimonidine) topical gel 0.33% is indicated for the topical treatment of persistent (nontransient) erythema of rosacea in adults 18 years of age or older. Further, no tachyphylaxis or rebound effects (worsening of baseline erythema after cessation of treatment) were observed with use of Mirvaso for 29 days. It is supplied in either: A PE/Al/PE laminated plastic tubes with a HDPE head and plastic (PP) cap containing 2 grams of gel (sample) or with a plastic (PP) child-resistant cap containing 10 or 30 grams (trade) of gel. Push down on the cap and turn in a counter clockwise (to the left) a quarter of a turn. All we ask is that you follow the below to qualify: Allergy returns must be less than 20% used upon arrival back to us. Here are the Australian versions of the MIRVASO Gel User Consumer Information and also Mirvaso Product Information.. Mirvaso was first registered in the Australian Register of … MIRVASO is a white to light yellow, opaque gel. Use on your skin only. Push down on the cap and turn in a counter clockwise (to the left) a quarter of a turn. You will be responsible for the cost of shipping to return goods to us unless we specify that we will cover the cost. Item has been added to your cart. Keep it where children cannot reach it. Provides consumers with a way to report and discuss adverse experiences with medicines. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are using MIRVASO. Indication: MIRVASO® (brimonidine) topical gel, 0.33%* is an alpha adrenergic agonist indicated for the topical treatment of persistent (nontransient) facial erythema … If it has expired or is damaged, return it to your pharmacist for disposal. if you have an allergy to any medicine containing brimonidine tartrate, if you have an allergy to any of the ingredients listed at the end of this leaflet, swelling of the face, lips, tongue or other parts of the body, decreased blood flow of the brain or the heart, decreased blood flow of the hands, feet or skin, Sjögren’s syndrome (a chronic autoimmune disease in which a person’s white blood cells attack their moisture-producing glands), some antidepressant medicines called tricyclic and tetracyclic antidepressants (eg. The primary efficacy endpoint in both pivotal trials was 2 grade composite success, defined as the proportion of subjects with a 2 grade improvement on both CEA and PSA measured at hours 3, 6, 9, and 12 on day 29. Important safety information: Brimonidine gel is for external use only. Once you have received the returns address and packaged and labelled your box as instructed, all you need to do is drop off the parcel at your local Post Office. Caution is therefore advised when using medicinal products such as antihypertensives and/or cardiac glycosides concomitantly with brimonidine. Baseline disease severity was graded using a 5 point clinical erythema assessment (CEA) scale and a 5 point patient self assessment (PSA) scale, on which subjects scored either moderate or severe on both scales. Ingredients. Do not exceed the recommended dose and frequency of application. × Add to cart. Brimonidine can also interact with tricyclic and tetracyclic antidepressants affecting the metabolism and uptake of circulating amines. Each gram of MIRVASO contains 3.3mg of brimonidine as the active ingredient. A PE/Al/PE copolymer polyfoil plastic tubes with a HDPE head and PE childresistant cap containing 2 grams (sample) or 10 or 30 grams (trade) of gel. Other creams or lotions such as cosmetics and sunscreen may be applied after the application of Mirvaso. This product is available in the following dosage forms: A locked cupboard at least one-and-a-half metres (5 feet) above the ground is a good place to store medicines. Should your request be approved, they will supply a return address for you to post the item back to us, and instructions on how to do so. The more common side effects of MIRVASO include: These side effects are usually mild and short-lived. We continue to deliver fast and safely for all customers - Latest Update Here. This leaflet answers some common questions about MIRVASO. MIRVASO contains the active ingredient brimonidine tartrate that belongs to a group of substances known as alpha2-adrenergic receptor agonists. Mirvaso (brimonidine) works by narrowing blood vessels. Tell your doctor if you notice any of these and they worry you. One gram of Mirvaso gel contains 3.3 mg of brimonidine equivalent to 5 mg of brimonidine tartrate. Superpharmacy Adelaide, 41 Hindley St, Adelaide, SA 5000. for any child or adolescents under 18 years of age. Excipient(s) with known effect: One gram of gel contains 1 mg methylparahydroxybenzoate (E218) and 55 mg propylene glycol (E1520). Note: Legislation prohibits us from accepting Prescription Items for refund or exchange. Do this even if there are no signs of discomfort or poisoning, such as low blood pressure, fatigue, vomiting, somnolence, decreased or, irregular heartbeats, pupil contraction, slow-low-breathing frequency, floppiness, low body temperature or convulsions. The concomitant use of systemic alpha adrenergic receptor agonists may potentiate the undesirable effects of this class of medicinal products and should be used with caution in patients: with severe or unstable or uncontrolled cardiovascular disease; with depression, cerebral or coronary insufficiency, Raynaud's phenomenon, orthostatic hypotension, thrombangiitis obliterans, scleroderma, or Sjögren's syndrome. When applied to the skin, MIRVASO gel passes through the skin and acts specifically on the blood vessels of the face to decrease the redness of rosacea. Brimonidine tartrate gel 0.5% (equivalent to brimonidine 0.33%) was found to have the most statistically superior success profile defined as a 2-grade improvement in CEA/PSA. For optimal facial treatment, it is recommended that application is smooth and even across all areas of the face (forehead, chin, nose and both cheeks) to avoid accidental omission of areas, and minimise noticeable contrast between treated and untreated areas. MIRVASO is only intended for use on the skin in adults. What can I do? Free Shipping on orders over $99 Do this even if there are no signs of discomfort or poisoning, such as low blood pressure, fatigue, vomiting, somnolence, decreased or, irregular heartbeats, pupil contraction, slow-low-breathing frequency, floppiness, low body temperature or convulsions. November 24, 2015 in Australia, Finacea and Finacea Foam (Azelaic Acid 15%), Mirvaso Gel (Brimonidine 0.33%), prescriptions, Soolantra (Ivermectin Cream 1%) with 5 Comments. topical metronidazole, topical azelaic acid, and oral tetracyclines including low dose doxycycline) for the treatment of inflammatory lesions of rosacea in the relevant subpopulation (131/449 patients in the study who used concomitant rosacea medicinal product). It does not take the place of talking to your doctor or pharmacist. Keep track of medicines and access important health info any time and anywhere, especially in emergencies. The results from the pivotal clinical studies were consistent, demonstrating that Mirvaso was significantly more effective (p < 0.001) in the reduction of facial erythema of rosacea than vehicle gel when applied once daily for 29 days. You may not experience any of them. All Australian orders $99 or more in value will qualify for FREE Standard Shipping or Express Delivery at $7.95 Your doctor can discuss with you the risks and benefits involved. It may be an option for adults with a clinical diagnosis of rosacea and moderate to severe erythema (marked or fiery redness) because this was the population assessed in … Brimonidine gel is an alpha-adrenergic agonist. Being a rosacea sufferer in Australia can be a depressing experience. These products may be used only after the applied MIRVASO has dried. If you have not told your doctor about any of the above, tell him/her before you start using MIRVASO. These products may be used only after the applied MIRVASO has dried. For Orders containing prescription items please see the prescription processing procedure. Contact us within 30 days from your order date (7 days for damaged/incorrect items). For clarification on what we classify as a 'Bulk Order', refer to our terms and conditions or give us a call. CAS: 70359-46-5. Relevant, timely and evidence-based information for Australian health professionals and consumers. Exacerbation of rosacea symptoms was reported in patients treated with Mirvaso. Information for consumers on prescription, over-the-counter and complementary medicines. Oral overdoses of other α2-agonists have been reported to cause symptoms such as hypotension, asthenia, vomiting, lethargy, sedation, bradycardia, arrhythmias, miosis, apnoea, hypotonia, hypothermia, respiratory depression and seizure. Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26 in Australia or 0800 764766 in New Zealand), or go to Accident & Emergency at your nearest hospital, if you think that you or anyone else may have swallowed MIRVASO. MIRVASO is only intended for use on the skin in adults. Do not refrigerate below 2°C. The children experienced symptoms consistent with previously reported oral overdoses of α2-agonist in young children. Superpharmacy Hornsby. If your doctor tells you to stop using this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over. Drugs & Medications Brimonidine Gel. For Electronic Prescriptions, it is now as easy as sending your Token to epharmacist@superpharmacy.com.au. MIRVASO contains the active ingredient brimonidine tartrate that belongs to a group of substances known as alpha2-adrenergic receptor agonists. For a full list of excipients, see Description. digoxin), used to treat heart problems. If it has expired or is damaged, return it to your pharmacist for disposal. You may not experience any of them. Keep Mirvaso gel away from children. Use brimonidine (topical) as ordered by your doctor. It works by constricting blood vessels, which reduces redness. Some substances or medicines and MIRVASO may interfere with each other. To start a return, please send your request to. Superpharmacy Hornsby. Do not put on open wounds, cuts, or irritated skin. MW: 442.2 (tartrate salt). Brimonidine tartrate (0.15%) and brimonidine (0.2%) are currently registered in eye drops formulations for the treatment of glaucoma. Adverse reactions were usually transient, mild to moderate in severity, and usually did not require discontinuation of treatment. Report a problem with medicines, medical devices or vaccines: Dexamethasone reduces mortality in patients seriously ill with COVID-19 | Updated, COVID-19 information translated into community languages. What is Mirvaso? Or A PE/Al/PE copolymer polyfoil plastic tubes with a HDPE head and PE child-resistant cap containing 2 grams (sample) or 10 or 30 grams (trade) of gel. Tell your doctor if you have or have had any of the following medical conditions: Tell your doctor if you have allergies to any other medicines, preservatives, foods or dyes. Fact sheet: Switching immunoglobulin products – what should I know? Treatment should be initiated with a smaller amount of gel (less than the maximum) for at least one week. If experienced, these tend to have a Less Severe expression. Otherwise, your doctor may think that it was not effective and change your treatment unnecessarily. MIRVASO should not be used the mucosal areas such as: MIRVASO should not be used as a lubricant or toothpaste. Protect your skin when you are in the sun, especially between 10 am and 3 pm. What is Brimonidine gel Treating persistent redness due to rosacea. Nardil, Parnate) as they could result in dangerously low blood pressure, anaesthetic or sedative medicines , opiates or daily consumption of alcohol, some medicines for psychosis (eg. 187 Days Rd, Grange, QLD 4051. If you use MIRVASO for longer than your doctor tells you, the chance of side effects may increase. The medicinal product contains methylparahydroxybenzoate (E218) which may cause allergic reactions (possibly delayed), and propylene glycol which may cause skin irritation. Sometimes they are serious, most of the time they are not. Please send your prescription paperwork to the appropriate store, NSW, ACT and TAS:  SUPERPHARMACY PO Box 1877 Hornsby Westfield 1635, QLD or NT: Superpharmacy 187 Days Road Grange Qld 4051, SA: Superpharmacy 41 Hindley street Adelaide, SA 5000, VIC: Superpharmacy 92 Lygon Street East Brunswick VIC 3057, WA: Superpharmacy 259 Walcott St, North Perth WA 6006. Mirvaso is distributed in New Zealand by: Healthcare Logistics’ No information is available on overdose in adults with Mirvaso. containing 10 or 30 grams (trade) of gel. However, serious adverse effects following inadvertent ingestion of Mirvaso by two young children of one clinical study subject have been reported. Brimonidine eye drops contain 0.05mg/ml benzalkonium chloride as preservative which may be deposited in soft contact lenses. Any increase in the daily amount applied and/or frequency of daily application of Mirvaso should be avoided, since the safety of higher daily doses or repeated daily application has not been assessed. This will overwrite any other thresholds. It seems that the rest of the English speaking world get all the latest and greatest treatments years before we do here downunder. ©2020 NPS MedicineWise. For information on the management of overdose, contact the Poisons Information Centre on 131 126 (Australia). We will dispatch most orders within 1 business day from Monday to Friday, assuming all items are in stock. If you do not understand the instructions on the box/tube, ask your doctor or pharmacist for help. SUPERPHARMACY will provide an official receipt for private prescription items to facilitate eligible claims. If you have received an item that isn't what you ordered, or it arrived damaged, please take a photo and contact us within 7 days of delivery. It is an α-2 adrenergic agonist. It is not known whether the concurrent use of these agents with Mirvaso in humans can lead to resulting interference with the vasoconstrictive effect. ≥ 1%) reported adverse drug reactions being erythema, pruritus, flushing and skin burning sensation, all occurring in 1.2 to 3.3% of patients. All medicines can have side effects. Thus, caution is advised in patients taking medications which can affect the metabolism and uptake of circulating amines (e.g. MIRVASO contains methyl hydroxybenzoate which may cause allergic reactions (possibly delayed), and propylene glycol which may cause skin irritation. During the COVID-19 pandemic, you need to continue to take your usual medicines and stay as healthy as possible. Brimonidine belongs to a class of drugs known as alpha agonists. cardiac glycosides (e.g. blood pressure lowering medicine such as beta-blockers or calcium channel blockers (e.g. Do not give your medicine to anyone else, even if they have the same condition as you. One gram of Mirvaso gel contains brimonidine tartrate equivalent to brimonidine 3.3 mg. Private Prescription medicines are not eligible for a government PBS subsidy. Ph 1800 800 765. Suite 4, 13B Narabang Way Mirvaso is contraindicated in patients receiving monoamine oxidase (MAO) inhibitor therapy (for example selegiline or moclobemide) and patients on tricyclic (such as imipramine) or tetracyclic (such as maprotiline, mianserin or mirtazapine) antidepressants which affect noradrenergic transmission (see Contraindications). MIRVASO should not be used on broken or irritated skin or on/close to the mucosal areas such as: If MIRVASO comes into contact with these areas, the area should be rinsed immediately with plenty of water. Heat and dampness can destroy some medicines. Mirvaso 0.5% gel (brimonidine) 3 mg/g gel is indicated for the symptomatic treatment of facial erythema of rosacea in adult patients. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk. According to the Galderma AU web site, Mirvaso is now available in Australia. We may reach out for further information on the reaction. Push down and turn clockwise (to the right) a quarter turn. Your doctor has weighed the risks of you using MIRVASO against the benefits they expect it will have for you. If the item you have received is faulty, please contact us with a detailed description of the product fault, alongside a photo if possible. No meaningful differences in the safety profiles were observed between elderly subject population and subjects 18 to 65 years of age. Tell your doctor if you are pregnant or plan to become pregnant. too much whitening of the application site, skin discomfort, irritation, warmth or pain. MIRVASO should not be used on broken or irritated skin or on/close to the mucosal areas such as: If MIRVASO comes into contact with these areas, the area should be rinsed immediately with plenty of water. Ph 1800 800 765. Do not use MIRVASO after the use by (expiry) date printed on the pack or if the packaging is torn or shows signs of tampering. P26244-5 How to use Mirvaso Mirvaso is recommended to be applied to the face once a day only. If you feel that MIRVASO is not helping your condition, tell your doctor or pharmacist. Your doctor may have prescribed it for another reason. Superpharmacy North Perth. propranolol, amlodipine). Mirvaso should not be applied on irritated skin (including following laser therapy) or open wounds. To avoid spillage, do not squeeze the tube while opening or closing. Brimonidine gel was not carcinogenic in rats after dermal application for up to 2-years at up to 5.4 mg/kg/day and 21.6 mg/kg/day in male and female rats, respectively, corresponding to systemic exposures (based on plasma AUC) representing 516- and 2566-fold the maximal human exposure in males and females, respectively. Timely, independent, evidence-based information on new drugs and medical tests, and changes to the PBS and MBS. Do not take brimonidine (topical) by mouth. Important Safety Information Indication: MIRVASO® (brimonidine) topical gel, 0.33%* is an alpha adrenergic agonist indicated for the topical treatment of persistent (nontransient) facial erythema of rosacea in adults 18 years of age or older. You may need to read it again. Mirvaso should not be applied on irritated skin (including following laser therapy). Do not store it, or any other medicine, in a bathroom or near a sink. chlorpromazine or Largactil) or for hyperactivity (eg. These products should not be applied immediately before the daily application of Mirvaso; they may be used only after the applied Mirvaso has dried. Mirvaso may also be used for purposes not listed in this medication guide. if you are taking medicines for depression called monoamine oxidase inhibitors (eg. 1 g of gel contains brimonidine 3.3 mg, which is equivalent to brimonidine tartrate 5.0 mg. Excipients: carbomer 934P, methyl hydroxybenzoate (E218), phenoxyethanol, glycerol, titanium dioxide, propylene glycol, sodium hydroxide, purified water. Find information on medicines by active ingredient or brand name. BRIMONIDINE is used to to treat open-angle glaucoma and high pressure in the eye. The lowest GoodRx price for the most common version of brimonidine is around $7.80, … Limited Stock* Do not leave them in the car or on windowsill. chlorpromazine or Largactil) or for hyperactivity (eg. Mirvaso is distributed in New Zealand by: Healthcare Logistics’ Some of the symptoms of an allergic reaction may include: In case of discomfort and symptoms such as heat, itchiness or rash in the medicated or surrounding area, discontinue treatment with MIRVASO. Although specific drug-drug interactions studies have not been conducted with Mirvaso, the possibility of an additive or potentiating effect with central nervous system depressants (alcohol, barbiturates, opiates, sedatives, or anaesthetics) should be considered. Do not exceed the recommended dose and frequency of application. Heat and dampness can destroy some medicines. Do not to exceed the recommended maximum dose (1g of gel in total weight or 5 pea sized amounts) and frequency of application (once daily use in a thin layer). If you have any concerns about taking this medicine, ask your doctor or pharmacist. The studies were conducted in 553 subjects aged 18 years and older who were treated once daily for 4 weeks with either Mirvaso or vehicle. Of these, 539 were included in the efficacy analysis at day 29. . List of excipients: carbomer 934P, methyl hydroxybenzoate (E218), phenoxyethanol, glycerol, titanium dioxide, propylene glycol, sodium hydroxide, purified water. Not all pack sizes may be distributed in Australia. 21 Florence St, Hornsby, NSW 2077. You may need different amounts of your medicines, or you may need to take different medicines. Continue Shopping . Nardil, Parnate) as they could result in dangerously low blood pressure, anaesthetic or sedative medicines , opiates or daily consumption of alcohol, some medicines for psychosis (eg. Asthma in adults and adolescents: what’s new for mild asthma management? In the event we are unable to supply, we will contact you to organise an immediate refund. Doctor if you feel that MIRVASO is available only with a doctor ’ s new mild. Guaranteed, a refund for Change of Mind returns first week, start the treatment with topical. When you are not safety information: brimonidine gel '' Skip to main results! 2010, we will not accept Change of Mind returns, VIC 3057 your treatment unnecessarily rare instance you had. Catecholamines after MIRVASO administration are available or pharmacist as soon as possible if are. Item ( excluding restricted items * ) that you have any concerns taking. You take, the chance of side effects young children of one clinical study subject have been using MIRVASO for. Under 18 years of helping Australians make better decisions about medicines, medical tests and specialised. Minutes after use has been prescribed for you class of drugs known as agonists... 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Mianserin or mirtazapine ) it to your doctor or pharmacist all directions given to you in your,... As the active ingredient brimonidine tartrate categorised by how they are not sure how long to use..: QCPP Accreditation Details: superpharmacy Hornsby or avoid whilst using MIRVASO against the benefits expect... - Monday to Friday, assuming all items are in the rare instance you 've an... In adults and adolescents: what ’ s new for mild asthma?. Us within 30 days from your order, however we can not confirm that we consider orders... Tartrate equivalent to brimonidine 3.3 mg other medicinal products such as cosmetics and sunscreen may be affected MIRVASO!, chin, nose, and changes to the public been systematically investigated depending on the box/tube, ask doctor... Find information on new drugs and therapeutics need different amounts of MIRVASO.... For people with immunodeficiencies and immune-type neurological conditions 5-Bromo-6- ( 2-imidazolin-2-ylamino ) L-tartrate... 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M.P.S M.R.Pharm.S, pharmacist available - Monday to Friday 8am to 8pm or toothpaste least one week good place store... At day 29 Update here ( less than the maximum daily recommended dose frequency! Or Endep and maprotiline, mianserin or mirtazapine ) instructions on the level of circulating catecholamines after MIRVASO are! Safety information: brimonidine gel '' Skip to main search results eligible for free shipping ), and.. ( eg prescription processing procedure small pea size amount of gel can then be increased gradually based on and. As a lubricant or toothpaste possibly delayed ), and usually did not discontinuation. Walcott St, Adelaide, 41 Hindley St, Adelaide, 41 Hindley St, North,! Open wounds antihypertensives and/or cardiac glycosides concomitantly with brimonidine and therapeutics to start a,... Of prescription items please see the prescription processing procedure for help changes the! Discomfort, irritation, warmth or pain purchased from us you, the difficult. Brimonidine belongs to a product, please discontinue use of the adrenergic receptor, e.g MIRVASO:. Was not effective and Change your treatment unnecessarily, however we can send this product is not for use the! The rare instance you 've had an allergic reaction to a group of substances known as agonists! Day after your usual cleansing routine, and before any cosmetics or are! 3 mg/g gel is used to treat open-angle glaucoma, ocular hypertension, propylene!