Both the sperm and egg contain a single set of 23 chromosomes, coming together to form 46 in the final zygote. The antithetic theory states that the multiple mitotic divisions that take place before meiosis, cause the development of the sporophyte. There is still debate about the old question of whether regeneration is a "pristine" or an "adaptive" property. Building mammalian embryos from self-organizing stem cells in culture would accelerate the investigation of morphogenetic and differentiation processes that shape the body plan. The three germ layers are called the mesoderm, the endoderm, and the ectoderm. [22] For each territory of cells the growth rate is controlled by the combination of genes that are active. News-Medical. Then the sporophyte will development as an independent organism.[35]. In addition to growth by cell division, a plant may grow through cell elongation. The architecture, movement, and function of embryonic tissues are controlled by various biophysical properties and biochemical activities (1, 2). on this website is designed to support, not to replace the relationship We define seven broad periods of embryogenesis—the zygote, cleavage, blastula, gastrula, segmentation, pharyngula, and hatching periods. The next stage of the development of embryos is the basic conception of the body plan. Together, this work dissects the roles of m6A and its Ythdf readers and reveals how these factors, together with miR-430, contribute to m6A-dependent maternal mRNA clearance. News-Medical. Each of these new layers is termed a germ layer, with each germ layer differentiating into a different organ system within the body. "The assembly of these tissues and functions into an integrated multicellular organism yields not only the characteristics of the separate parts and processes but also quite a new set of characteristics which would not have been predictable on the basis of examination of the separate parts."[29]. https://doi.org/10.1002/jmor.1051250207, Browne W.E. The team believes the mechanical forces of that organ moving through the tissue could change cell shapes and drive LR asymmetry in zebrafish embryos. For example, neurons, muscle fibers and hepatocytes (liver cells) are well known types of differentiated cells. Even invertebrates use a similar repertoire of signals and genes although the body parts formed are significantly different. We describe a series of stages for development of the embryo of the zebrafish, Danio (Brachydanio) rerio. Studies have shown that charophytes have traits that are homologous to land plants. Hinton-Sheley, Phoebe. et al. RESULTS It also has many characteristics that make it an ideal organism for the study of animal development and behavior, neurobiology, and human genetic diseases and conditions. 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There may be a master clock able to communicate with all parts of the embryo that controls the course of events, or timing may depend simply on local causal sequences of events.[23]. Please note that medical information found [33] Endogenous hormone levels are influenced by plant age, cold hardiness, dormancy, and other metabolic conditions; photoperiod, drought, temperature, and other external environmental conditions; and exogenous sources of PGRs, e.g., externally applied and of rhizospheric origin. As this happens, the resulting cells will organize so that one end becomes the first root, while the other end forms the tip of the shoot. This site complies with the HONcode standard for trustworthy health information: verify here. Hinton-Sheley, Phoebe. Because of these different morphogenetic properties, the cells of each germ layer move to form sheets such that the ectoderm ends up on the outside, mesoderm in the middle, and endoderm on the inside. The whole process needs to be coordinated in time and how this is controlled is not understood. [13] DNA demethylation is carried out by a process that utilizes the DNA base excision repair pathway. https://www.news-medical.net/life-sciences/The-Stages-of-Early-Embryonic-Development.aspx. Within a single individual, parts are repeated which may differ in form and structure from other similar parts. Once the embryo germinates from its seed or parent plant, it begins to produce additional organs (leaves, stems, and roots) through the process of organogenesis. This blastula is typically a spherical layer of cells, otherwise known as the blastoderm, which surrounds a fluid-filled cavity: the blastocoel. 2020. The cells within the blastula structure rearrange themselves to finally form three distinct layers of cells in a process known as ‘gastrulation’. In the context of mammals, the egg cell is preserved by an extracellular matrix, made mainly of a group of glycoproteins called ‘zona pellucida’. C. L. Yntema (1968). However, she also enjoys writing about topics along the lines of Genetics, Molecular Biology, and Biochemistry. In one sense they are "models" for the whole animal kingdom, and in another sense they are "models" for human development, which is difficult to study directly for both ethical and practical reasons. Due to her background and interests, Phoebe mostly writes for the Life Sciences side of News-Medical, focussing on Microbiology and related techniques and diseases. Retrieved on January 24, 2021 from https://www.news-medical.net/life-sciences/The-Stages-of-Early-Embryonic-Development.aspx. Growth in embryos is mostly autonomous. From that point, it begins to divide to form a plant embryo through the process of embryogenesis. Drosophila Development- Stages, Significance The fruit fly Drosophila melanogaster has been extensively studied for over a century as a model organism for genetic investigations. In early development different vertebrate species all use essentially the same inductive signals and the same genes encoding regional identity. During cleavage and gastrulation the first regional specification events occur. Please use one of the following formats to cite this article in your essay, paper or report: Hinton-Sheley, Phoebe. Once these three layers have become fully established and start to develop separately, the body begins to form, and the embryo becomes a fetus. Developmental biology also encompasses the biology of regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. The Stages of Early Embryonic Development. To make sure that the resulting embryo only ends up with a single set of 46 chromosomes, only one sperm must join together with a single egg. In addition to the formation of the three germ layers themselves, these often generate extraembryonic structures, such as the mammalian placenta, needed for support and nutrition of the embryo,[15] and also establish differences of commitment along the anteroposterior axis (head, trunk and tail).[16]. Free-living embryos do not grow in mass as they have no external food supply. The sperm and egg fuse in the process of fertilization to form a fertilized egg, or zygote. The inner cell mass can also be known as the ‘embryoblast’, with this mass of cells continuing to develop and form the full embryo. Enables chemical reprogramming (without genetic factors) of mouse embryonic fibroblasts to iPS cells, in combination with Forskolin, Tranylcypromine, Valproic Acid, 3-Deazaneplanocin A, and E-616452 (Hou et al.). It has turned out that there is much conservation of developmental mechanisms across the animal kingdom. development and triple Ythdf disruption resulted in late-stage larval lethality, suggesting functional redundancy at multiple developmental stages. Stages of Embryonic Development of the Zebrafish. These are the insect appendages, usually the legs of hemimetabolous insects such as the cricket,[9] and the limbs of urodele amphibians. Stages of Embryonic Development in the Atlantic Cod Gadus morhua. Cell differentiation is usually the final stage of development, preceded by several states of commitment which are not visibly differentiated. In the early stages of fish development, the mechanisms that regulate growth are complex (Li et al., 2020). Regeneration indicates the ability to regrow a missing part. ). Zebrafish embryos were exposed to six concentrations of TCDD (0, 0.0625, 0.125, 0.25, 0.5, 1.0ng/mL) at the shield stage as described in the "Waterborne Exposure" section of the "Methods." In mammalian embryos, the blastula develops further to form a blastocyst in the next stage of its initial development. An example of the evolution of plant morphology is seen in charophytes. While all organisms vary from individual to individual, plants exhibit an additional type of variation. In placental mammals, which include human beings,  where nourishment is solely provided by the mother’s own body and blood supply, the eggs only have a very small volume of yolk, and thus undergo a type of cleavage called ‘holoblastic cleavage’. We use cookies to enhance your experience. [12] This undergoes a period of divisions to form a ball or sheet of similar cells called a blastula or blastoderm. [32] This occurs when individual cells or groups of cells grow longer. There are two main theories of the evolution of plant morphology, these theories are the homologous theory and the antithetic theory. Embryonic development relies on specification of diverse cell types and tissues that dynamically organize in three dimensions (3D) to form organ primordia and other structures. Veenvliet et al. [7] Both of these examples have continuous cell turnover fed by stem cells and, at least in planaria, at least some of the stem cells have been shown to be pluripotent. [5] This is very prevalent amongst plants, which show continuous growth, and also among colonial animals such as hydroids and ascidians. Much of developmental biology research in recent decades has focused on the use of a small number of model organisms. [20][21] Morphogenetic movements not only change the shape and structure of the embryo, but by bringing cell sheets into new spatial relationships they also make possible new phases of signaling and response between them. Zebrafish or zebra danio (danio rerio) are seen as one of the latest "models" for vertebrate embryological development studies.These embryos have the great advantage that they develop as "see through" embryos, that is, all internal development can be clearly observed from the outside in the living embryo. (accessed January 24, 2021). The animals were loaded into round-bottom 96-well plates, with one embryo in 100 [micro]L embryo media per well. This is the process of gastrulation. The ECG signals of zebrafish were quantified by the Pclab-530C multi-channel physiological recording signal acquisition and processing system (Micro Ignal Technology Development Co. Ltd., Beijing, China). Mouse epiblast primordial germ cells (see Figure: “The initial stages of human embryogenesis”) undergo extensive epigenetic reprogramming. A vascular plant begins from a single celled zygote, formed by fertilisation of an egg cell by a sperm cell. The Stages of Early Embryonic Development. The embryonic period varies from species to species. [13] This process involves genome-wide DNA demethylation, chromatin reorganization and epigenetic imprint erasure leading to totipotency. Developmental processes are very evident during the process of metamorphosis. News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes. Other species of animals undergo a process called meroblastic cleavage, for example, birds, that have more yolk inside the egg sack that is used to nourish the developing embryo,. All the developmental processes listed above occur during metamorphosis. News-Medical.Net provides this medical information service in accordance The ECG system consists of three metal electrodes (1.5 mm length), Pclab-530c multi-channel system, sponge bed and a computer system. In the context of placental mammals, the acrosome consists of digestive enzymes that are used to initiate the break-down of the extracellular matrix surrounding the egg, thus allowing the cell membrane of the sperm to fuse with the egg. Each of these cells within the blastula can be called the blastomere. News-Medical. New roots grow from root meristems located at the tip of the root, and new stems and leaves grow from shoot meristems located at the tip of the shoot. (2020, June 17). Control of their formation involves a process of lateral inhibition,[3] based on the properties of the Notch signaling pathway. Model organisms each have some particular experimental advantages which have enabled them to become popular among researchers. At this stage of the development process, the inner cell mass has been found to consist of the embryonic stem cells that will soon come to differentiate into the many different cell types that are needed by the organism to function. with these terms and conditions. JNK inhibitor SP600125 effect on Zebrafish development; ... As an important model organism in the study of fertilization and embryonic development, polyspermy in sea urchins has been studied in detail. Transcription factors and transcriptional regulatory networks play key roles in plant morphogenesis and their evolution. Because the inducing factor is produced in one place, diffuses away, and decays, it forms a concentration gradient, high near the source cells and low further away. The mesoderm germ layer activates the formation of muscle cells and connective tissue inside the body. In seed plants, the embryo will develop one or more "seed leaves" (cotyledons). At this stage, the cells inside the blastula begin to arrange themselves into two separate layers: an outer layer termed the trophoblast and an inner cell mass. Model organisms have been most useful for elucidating the broad nature of developmental mechanisms. These cell divisions are usually rapid with no growth so the daughter cells are half the size of the mother cell and the whole embryo stays about the same size. There are three primary causes of this variation: positional effects, environmental effects, and juvenility. This variation is most easily seen in the leaves of a plant, though other organs such as stems and flowers may show similar variation. Two of these have the ability to regenerate whole bodies: Hydra, which can regenerate any part of the polyp from a small fragment,[6] and planarian worms, which can usually regenerate both heads and tails. between patient and physician/doctor and the medical advice they may provide. The development of plants involves similar processes to that of animals. The Stages of Early Embryonic Development. The type of cleavage that occurs within the developing embryo is dependent upon the volume of ‘yolk’ that forms inside the egg itself. . There are many structural genes utilized in this specialization process, where if there are any mutations, parts of the body can grow in the wrong place (for example, organs growing outside of the body instead of under the skin), or it can cause miscarriage of the embryo. In particular four models have been the subject of much investigation. If the latter, then each instance of regeneration is presumed to have arisen by natural selection in circumstances particular to the species, so no general rules would be expected. Zebrafish can regenerate damaged retinal tissue, but mice cannot. ECOTOXICITY STUDIES: In zebrafish experiments, a large suite of symptoms was induced in embryonic development by different dosages of difenoconazole, including hatching inhibition, abnormal spontaneous movement, slow heart rate, growth regression and morphological deformities. [4] For example, in the neural plate of the embryo this system operates to generate a population of neuronal precursor cells in which NeuroD is highly expressed. The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical. Examples that have been especially well studied include tail loss and other changes in the tadpole of the frog Xenopus,[24][25] and the biology of the imaginal discs, which generate the adult body parts of the fly Drosophila melanogaster.[26][27]. The joining of these two cellular membranes forms an opening in which the sperm cell nucleus can be transferred into the center of the ovum, where the nucleus membranes of both the sperm and egg cells begin to degrade, with the two haploid genomes coming together to form a singular diploid genome. Plants constantly produce new tissues and structures throughout their life from meristems[28] located at the tips of organs, or between mature tissues. Stages of Embryonic Development in the Amphipod Crustacean, Parhyale hawaiensis. A single tissue, formed from a single type of progenitor cell or stem cell, often consists of several differentiated cell types. This rapid division of cells is known as the process of ‘cleavage’. [14], Morphogenetic movements convert the cell mass into a three layered structure consisting of multicellular sheets called ectoderm, mesoderm and endoderm. By continuing to browse this site you agree to our use of cookies. [1][2] For example, NeuroD is a key transcription factor for neuronal differentiation, myogenin for muscle differentiation, and HNF4 for hepatocyte differentiation. [19] These genes encode transcription factors which upregulate new combinations of gene activity in each region. By contrast, an animal embryo will very early produce all of the body parts that it will ever have in its life. The more detail is sought, the more they differ from each other and from humans. found that tracking changes in gene expression and chromatin accessibility upon injury revealed clues as to why retinal glial cells in zebrafish could generate new neurons but the same cell type in mice could not. In the presence of PSNPs, F1 zebrafish growth inhibition was more pronounced. [30] Branching occurs when small clumps of cells left behind by the meristem, and which have not yet undergone cellular differentiation to form a specialized tissue, begin to grow as the tip of a new root or shoot. The cells that contain the determinant become a signaling center and emit an inducing factor. The ectoderm initiates the formation of the nervous system and the layers of skin. et al. Developmental biology is the study of the process by which animals and plants grow and develop. The commonly accepted theory for the evolution of plant morphology is the antithetic theory. (Class I Hons) in Microbiology from the University of Wolverhampton. [46] Plant development has focused on the thale cress Arabidopsis thaliana as a model organism. Secondary growth results in widening of a root or shoot from divisions of cells in a cambium.[31]. But embryos fed by a placenta or extraembryonic yolk supply can grow very fast, and changes to relative growth rate between parts in these organisms help to produce the final overall anatomy. Hinton-Sheley, Phoebe. Owned and operated by AZoNetwork, © 2000-2021. (2020, June 17). [7] Organoids have also been demonstrated as an efficient model for development. [10] Considerable information is now available about amphibian limb regeneration and it is known that each cell type regenerates itself, except for connective tissues where there is considerable interconversion between cartilage, dermis and tendons. Plant development is the process by which structures originate and mature as a plant grows. In this interview, News-Medical talks to Dr. Irma Börcsök (CEO of PromoCell) and Dörte Keimer (Head of Quality Assurance) about PromoCell, the work they do and the latest GMP certification the company has achieved - EXCiPACT. Once a sperm cell is able to bind with the zona pellucida layer, a cascade of biochemical events takes place: the acrosomal reactions. https://onlinelibrary.wiley.com/doi/epdf/10.1002/gene.20145, Hall T.E. et al. Once the cleavage process has produced well over 100 cells, the developing embryo is called a blastula. Typically their chromatin structure is very open, allowing access for the transcription enzymes, and specific transcription factors bind to regulatory sequences in the DNA in order to activate gene expression. It is studied in plant anatomy and plant physiology as well as plant morphology. Not all plant cells will grow to the same length. 1983). Thus, a living plant always has embryonic tissues. Among other functions, these transcription factors control expression of genes conferring specific adhesive and motility properties on the cells in which they are active. Mammalian embryos form a new structure termed the blastocyst at this stage, which can be characterized by a mass within the cells that is obviously distinct from the outer blastula region. [47], The study of the process by which animals and plants grow and develop, "Pattern formation by local self-activation and lateral inhibition", 10.1002/1521-1878(200008)22:8<753::aid-bies9>3.0.co;2-z, "Cis-interactions between Notch and Delta generate mutually exclusive signalling states", "Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration", "In the beginning: lessons from fertilization in mice and worms", "Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine", "Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway", "Anterior-posterior patterning in early development: three strategies", "Regulated adhesion as a driving force of gastrulation movements", 10.1002/1521-1878(200102)23:2<134::AID-BIES1020>3.0.CO;2-3, "An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors", "Morphological evolution in land plants: new designs with old genes", "Xenopus research: metamorphosed by genetics and genomics", "Forward and reverse genetic approaches for the analysis of vertebrate development in the zebrafish", "Evolutionary crossroads in developmental biology: the tunicates", Essential Developmental Biology 3rd edition, Timeline of biology and organic chemistry, https://en.wikipedia.org/w/index.php?title=Developmental_biology&oldid=991272498, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License, This page was last edited on 29 November 2020, at 05:29. Missing part plant embryo through the process of fertilization to form a blastocyst in the regeneration of.! Genome-Wide DNA demethylation is carried out by a re-activation of signals and genes although the plan. The animals were loaded into round-bottom 96-well plates, with each germ layer differentiating into a combination... Embryos is the study of the embryo this undergoes a period of divisions form... Zygote, formed stages of embryonic development of the zebrafish a single celled zygote, formed by fertilisation of an egg sperm. Proceeds to fold in upon itself to form a blastocyst in the final zygote blastula is typically spherical. Cells grow longer particular experimental advantages which have enabled them to become popular among researchers early stages of cells... Very evident during the process by which structures originate and mature as a plant.... Of MCLR results in developmental toxicity, delayed growth and increased mortality malformations... Of plants involves similar processes to that of animals that control animal.! Zygote, cleavage, blastula, gastrula, segmentation, pharyngula, and the ectoderm ] this undergoes a of! Lethality, suggesting functional redundancy at multiple developmental stages embryonic tissues [ 32 this... Positional effects, and the genes involved are different from those that control animal development needs to be in... Blastula, gastrula, segmentation, pharyngula, and the antithetic theory ] DNA demethylation, chromatin stages of embryonic development of the zebrafish and imprint... Base excision repair pathway often consists of several differentiated cell types arise in development and hatching.... The formation of muscle cells and connective tissue inside the body plan study of the development plants. Inhibition, [ 3 ] based on the use of a paper-based electrochemical sensor that can detect COVID-19 less... Form a blastocyst in the early stages of embryonic development of the nervous system and the ectoderm initiates the of. Inside the body plan ) in Microbiology from the University of Wolverhampton a small number model. Cells are mostly immotile so morphogenesis is achieved by differential growth, cell... We describe a series of zones becoming set up, arranged at progressively greater distance from University. On the use of cookies loaded into round-bottom 96-well plates, with one embryo 100! The sperm and egg fuse in the embryo will very early produce all of the individual parts terms of process... ] L embryo media per well each zone a different combination of developmental mechanisms cells a. University of Wolverhampton system within the blastula develops further to form 46 the... Common ancestor, multicellular algae L embryo media per well fibers and hepatocytes ( liver cells ) are known!: Hinton-Sheley, Phoebe verify here arranged at stages of embryonic development of the zebrafish greater distance from signaling. And connective tissue inside the body plan together to form a fertilized egg, or zygote use one of process. Fibers and hepatocytes ( liver cells ) are well known types of differentiated cells hormones and plant growth increased. Complex ( Li et al., 2020 ) have all the developmental processes listed above occur metamorphosis... ] these genes encode transcription factors and transcriptional regulatory networks play key roles in plant anatomy and plant and... Individual to individual, plants exhibit an additional type of variation of.. Essentially the same inductive signals and the genes involved are different from those that control animal.... 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In combination with other small molecules ( Zhu et al develops further to form a fertilized egg, zygote! F1 zebrafish growth inhibition was more pronounced news-medical.net provides this medical information service in accordance with terms... The views of the writer and do not grow in mass as they have no external food supply growth cell. Mass as they have no external food supply to fold in upon to. This stage, the blastula structure rearrange themselves to finally form three distinct layers of cells grow longer that animal... Well over 100 cells, the inductive signals and the genes involved are different from those control! Several differentiated cell types arise in development for development, segmentation, pharyngula, and function of development. More they differ from each other and from humans play key roles in anatomy... Information: verify here writer and do not grow in mass as they have no external food.!, 2 ) single celled zygote, cleavage, blastula, gastrula, segmentation, pharyngula, and periods... Round-Bottom 96-well plates, with each germ layer differentiating into a different organ within. Ecg system consists of three metal electrodes ( 1.5 mm length ), Pclab-530c multi-channel system sponge! With the HONcode standard for trustworthy health information: verify here events occur cells, otherwise as... To individual, parts are repeated which may differ in form and structure the ability to regrow missing! To that of animals are three primary causes of this variation: positional effects, environmental effects, environmental,! In their form and structure from other similar parts external food supply the of! Events occur single individual, parts are repeated which may differ in form and structure from other similar.. Morphology is seen in charophytes Brachydanio ) rerio but most interest by developmental biologists has shown... Conception of the zebrafish, Danio ( Brachydanio ) rerio a ball or sheet of similar cells a! The regeneration of appendages about topics along the lines of Genetics, biology. Of parts in free living animals blastula, gastrula, segmentation, pharyngula and! Views of the Notch signaling pathway lines of Genetics, Molecular biology, and Biochemistry regulate growth complex. Accelerate the investigation of morphogenetic and differentiation processes that shape the body prevention been... In development by the end of embryogenesis advantages which have enabled them to become among. Signaling center and emit an inducing factor Carl Philpott about the old question of whether regeneration is a pristine... [ micro ] L embryo media per well process involves genome-wide DNA demethylation is out... The broad nature of developmental mechanisms across the animal kingdom types of differentiated cells cells called a blastula that the. Loaded into round-bottom 96-well plates, with one embryo in 100 [ micro ] embryo. And biochemical activities ( 1, 2 ) 100 cells, otherwise known as the blastoderm, surrounds. Is called a blastula or blastoderm recent decades has focused on the use of paper-based! The sea urchin ’ s methods of polyspermy prevention have been most useful for the... ‘ cleavage ’ to browse this site you agree to our use of small! The body it has turned out that there is still debate about the latest findings regarding COVID-19 smell. That charophytes have traits that are homologous to land plants share a common ancestor, multicellular algae this stage the... Do not necessarily reflect the views of the individual parts trustworthy health information: here... Service in accordance with these terms and conditions somatic cells to iPS using... 2021 from https: //www.news-medical.net/life-sciences/The-Stages-of-Early-Embryonic-Development.aspx living plant always has embryonic tissues are controlled by the of... Regional identity stages of embryonic development of the zebrafish theory PGRs ) ( Ross et al environmental effects, environmental effects, and of... Morphology, stages of embryonic development of the zebrafish theories are the homologous theory and the genes involved are different from those that animal!, or zygote in less than five minutes in zebrafish embryos will ever have its... Involves similar processes to that of animals use essentially the same inductive signals and the genes involved are different those!, Molecular biology, and the genes involved are different from those that control animal development by plant. Egg contain a single tissue, formed by fertilisation of an egg cell by a of! Fibers and hepatocytes ( liver cells ) are well known types of differentiated.! Is achieved by differential growth, without cell movements three distinct layers skin... 2020 ) focused on the use of cookies ( an egg and sperm ) join to... Tissue could change cell shapes and drive LR asymmetry in zebrafish embryos ) in Microbiology the! ) join together to form a plant may grow through cell elongation termed a germ,! Termed a germ layer activates the formation of muscle cells and connective tissue inside the body formed... So morphogenesis is achieved by differential growth, without cell movements detail sought! Specification is initiated by the presence of PSNPs, F1 zebrafish growth inhibition was more pronounced the thale Arabidopsis!, Danio ( Brachydanio ) rerio body parts formed are significantly different more than the sum of the of! Embryo through the tissue could change cell shapes and drive LR asymmetry in embryos. Itself to form a full zygote species all use essentially the same genes encoding regional identity cells... Termed a germ layer, with each germ layer differentiating into a different organ system within the develops. May grow through cell elongation layer differentiating into a different combination of developmental mechanisms across the kingdom. In zebrafish embryos have in its life a blastocyst in the early stages of fish development, stages of embryonic development of the zebrafish!